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A re-evaluation of anticholergic premedication
Canadian Anaesthetists' Society Journal
|January 1, 1977
Summary
Intravenous atropine at anesthesia induction is preferred over intramuscular administration for gynecological surgery. This method avoids injection timing issues and reduces patient discomfort from dry mouth, offering a more convenient option.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Atropine is commonly used for premedication in anesthesia.
- The route of administration can impact patient experience and drug efficacy.
Purpose of the Study:
- To compare the efficacy and patient experience of intramuscular versus intravenous atropine as a premedication for minor gynecological operations.
Main Methods:
- 120 healthy Nigerian female patients were randomized into two groups.
- Group 1 received intramuscular atropine on the ward; Group 2 received intravenous atropine at induction.
- Anesthesia was induced with thipentone and maintained with nitrous oxide, oxygen, and halothane via facemask.
Main Results:
- Both administration routes provided satisfactory control of secretions.
- Intramuscular atropine administration faced occasional timing difficulties.
- 87.7% of patients receiving intramuscular atropine reported uncomfortable dry mouth.
Conclusions:
- Intravenous atropine administration at induction is preferable due to easier timing and reduced patient-reported dry mouth.
- This route also eliminates the need for an additional injection for the patient.