Related Experiment Video
Updated: Aug 9, 2026

Measurement of Aggregate Cohesion by Tissue Surface Tensiometry
Published on: April 8, 2011
Calibration of a compaction simulator for the measurement of tablet thickness during compression
1SmithKline Beecham Pharmaceuticals, Pharmaceutical Sciences Department, King of Prussia, Pennsylvania 19406.
Abstract:
For the calibration of a compaction simulator for punch displacement measurements, the displacement of the punch must be related to the voltage output of a linear variable displacement transducer (LVDT) which is attached to the punch via its movable core, with correction for any deformation of the machine parts which are inherently incorporated in the LVDT readings. Contrary to common assumptions the relationship between the displacement of the movable core and the voltage output of the LVDTs used is not linear. Similarly, the deformation of the machine parts did not follow Hooke's law of linear elasticity but exhibited characteristics of nonlinear elasticity. The data demonstrate the need for careful validation of the calibration of a compaction simulator when accurate punch displacements are required.
Related Concept Videos
Glassware Calibration
Volumetric flasks: Volumetric flasks are designed to prepare aqueous solutions of precise volumes accurately with a calibration line on the neck. To calibrate a volumetric flask, it is important to fill it with distilled...
Slump Test
Concrete is poured into the mold in three layers to conduct the test. Each layer is compacted 25 times with a steel tamping rod, which has a five-eighths-inch diameter and a rounded end, to ensure even distribution and eliminate...
Compacting Factor test
The procedure begins by placing concrete into the upper hopper without any compaction. Once filled, the bottom door of this hopper is opened,...
Vebe Test
To conduct the test, concrete is placed into the slump cone. The concrete is filled in layers and...
In Vitro Drug Dissolution: Compendial Testing Models I
In Vitro Drug Dissolution: Compendial Testing Models II

