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High-dose chlorambucil and dexamethasone for relapsed non-Hodgkin's lymphomas
G Joseph1, T Hadley, B Djulbegovic
1Division of Medical Oncology, University of Louisville School of Medicine, Kentucky.
American Journal of Clinical Oncology
|August 1, 1993
Abstract:
Twenty patients with relapsed or refractory non-Hodgkin's lymphoma were treated with high-dose chlorambucil (14 mg/m2 every 6 hours for 6 doses) and dexamethasone (40 mg/day for 5 days). There was a 45% response rate with 17% complete responses. The median duration of complete response was 7 months. The regimen was well tolerated and had minimal toxicity.