Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paroxysmal alien hand syndrome

R Leiguarda1, S Starkstein, M Nogués

  • 1Institute of Neurological Research, Raúl Carrea, Buenos Aires, Argentina.

Journal of Neurology, Neurosurgery, and Psychiatry
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Lambert-Eaton myasthenic syndrome].

Revista de neurologia·2021
Same author

Vasculitic Peripheral Neuropathy, Differences Between Systemic and Non-Systemic Etiologies: A Case Series and Biopsy Report.

Journal of neuromuscular diseases·2020
Same author

Geometry of color perception. Part 2: perceived colors from real quantum states and Hering's rebit.

Journal of mathematical neuroscience·2020
Same author

The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.

Translational medicine @ UniSa·2019
Same author

Atraumatic laparoscopic intraperitoneal mesh fixation using a new laparoscopic device: an animal experimental study.

Hernia : the journal of hernias and abdominal wall surgery·2019
Same author

Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project).

Allergy·2017
Same journal

Diagnostic accuracy of a two-cut-off approach using the FAQ/MMSE ratio and FAQ for clinical preselection of patients for anti-amyloid therapy.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Cancer risk and mortality in patients with multiple sclerosis in Finland: a retrospective population-based cohort study.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Visuospatial working memory in Huntington's disease: behavioural and structural brain correlates.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Characteristics and outcomes in electric scooter-related traumatic brain injuries in Helsinki.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Chronological ageing and ovarian reserve in MS: insights from anti-Müllerian hormone and disability progression.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Durable fluoropolymer drug-eluting stent versus bare-metal stent for the prevention of intracranial in-stent restenosis.

Journal of neurology, neurosurgery, and psychiatry·2026
See all related articles

This study describes a paroxysmal alien hand syndrome. Patients experienced brief episodes of involuntary, foreign-feeling arm movements or a loss of awareness and recognition of their own limb.

Area of Science:

  • Neuroscience
  • Neurology

Background:

  • Alien hand syndrome (AHS) is a rare neurological disorder.
  • Typically, AHS involves involuntary, uncontrolled movements of a limb.
  • Previous cases have been linked to specific brain lesions.

Observation:

  • Four patients presented with paroxysmal (sudden, brief) episodes resembling AHS.
  • Two patients had frontomedial cortex damage, exhibiting groping and grasping movements.
  • Two patients with posterior parietal damage reported unawareness, non-recognition, and personification of their arm.

Findings:

  • This study identifies a novel, paroxysmal form of alien hand syndrome.
  • Lesions in different brain regions (frontomedial vs. posterior parietal) produced distinct AHS manifestations.
  • The paroxysmal nature suggests potential ictal (seizure-related) mechanisms.

Related Experiment Videos

Implications:

  • These findings expand the clinical spectrum of alien hand syndrome.
  • Understanding these variants aids in diagnosing and localizing brain dysfunction.
  • Further research into ictal mechanisms may reveal new therapeutic targets for AHS.