[Lysozyme level in animal tissues in the simulation and treatment of periodontitis]

Inflammation developed after sewing of silk ligature into the rat and rabbit gingiva (parodonitis) was accompanied by increase in lysozyme content in gingiva tissue and in blood serum. Exogenous egg lysozyme, administered into normal animal gingiva tissue by means of ultrasound treatment (880 kHz, impulse regimen, 0.2 w/cm2), penetrated through the epithelial mucosal membrane layer, but did not accumulate in the membrane. However, lysozyme administered into the inflammation-injured gingiva tissue by ultrasound was accumulated in the tissue and arrested the inflammation and restored the impaired parodontium within shorter periods.