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[Thrombolytic therapy in the past, present and future]
1Klinikum Rudolf Virchow, Franz-Volhard-Klinik & Max-Delbrück-Zentrum für Molekulare Medizin, Freien Universität Berlin.
Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|June 1, 1993
Summary
Thrombolytic therapy has evolved from an experimental approach to a standard treatment for acute myocardial infarction. This success has spurred its use in other thromboembolic diseases, highlighting its growing importance in clinical practice.
Area of Science:
- Cardiovascular Medicine
- Hematology
- Pharmacology
Background:
- Thrombolysis has transformed from an experimental method to a cornerstone treatment for acute myocardial infarction over the past decade.
- This significant advancement has inspired the exploration and application of thrombolytic techniques in various other thromboembolic conditions.
Purpose of the Study:
- To provide a concise overview of the historical development of thrombolysis.
- To discuss the current status and future prospects of thrombolytic therapy in clinical practice.
Main Methods:
- Historical review of thrombolytic therapy.
- Summary of key milestones in thrombolysis research and application.
Main Results:
- The discovery of fibrinolysin in 1933 marked the beginning of thrombolysis research.
- Thrombolysis is now a well-established and effective treatment for acute myocardial infarction.
Conclusions:
- The evolution of thrombolysis demonstrates its increasing significance in managing thromboembolic diseases.
- Future research will likely expand the therapeutic applications of thrombolytic agents.