Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Accommodative response changes with age measured by pattern electroretinogram

N Toyonaga1, E Adachi-Usami

  • 1Department of Ophthalmology, Chiba University School of Medicine, Japan.

Documenta Ophthalmologica. Advances in Ophthalmology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes of macular and RNFL thicknesses measured by Stratus OCT in patients with early stage diabetes.

Eye (London, England)·2008
Same author

Use of blue-on-yellow perimetry for detection of sectoranopia.

Eye (London, England)·2004
Same author

Relative hypersensitivity in healthy eye by frequency doubling perimetry in patients with severely damaged contralateral eye.

The British journal of ophthalmology·2003
Same author

Optic disc metastasis presenting as an initial sign of recurrence of adenoid cystic carcinoma of the larynx.

Eye (London, England)·2003
Same author

Criteria for early detection of temporal hemianopia in asymptomatic pituitary tumor.

Eye (London, England)·2002
Same author

Fish oil (polyunsaturated fatty acid) prevents ischemic-induced injury in the mammalian retina.

Experimental eye research·2002
Same journal

Effects of short-term moderate versus high intraocular pressure elevation on flicker-induced changes in full-field electroretinogram.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

The relationship between foveal anatomy and retinal function in oculocutaneous albinism.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Early onset primary angle closure and foveal retinoschisis associated with a pseudo-homozygous CRB1 pathogenic variant.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Bilateral perifoveal macular ischemia in non-proliferative Duchenne muscular dystrophy-associated retinopathy: a case report.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Association between dynamic pupil parameters and corneal sub-basal nerve plexus morphology.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Structure-function relationship between handheld photopic negative response and macular GCIPL thickness in chronic optic neuropathy.

Documenta ophthalmologica. Advances in ophthalmology·2026
See all related articles

Transient pattern electroretinograms (tPERG) can reflect the eye's accommodative response. The P-N amplitude increases with accommodative stimulus up to 4 diopters, then decreases, especially in older individuals.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Physiology

Background:

  • The transient pattern electroretinogram (tPERG) is a diagnostic tool used in ophthalmology.
  • Accommodation is the eye's ability to change focus from distant to near objects.

Purpose of the Study:

  • To determine if the tPERG's P-N component amplitude correlates with the accommodative response.
  • To investigate how age affects the accommodative response measured by tPERG.

Main Methods:

  • Normal volunteers underwent tPERG testing with a reversing checkerboard pattern.
  • Ophthalmic lenses of varying diopter powers were used to alter the accommodative stimulus.
  • The P-N amplitude of the tPERG was recorded and plotted against the accommodative stimulus, both with and without cycloplegia.

Related Experiment Videos

Main Results:

  • tPERG P-N amplitude showed a rapid increase up to approximately 4 diopters of accommodative stimulus, followed by a gradual decrease.
  • This decrease became more pronounced under cycloplegic conditions.
  • The amplitude of accommodative response significantly attenuated in subjects over 40 years old.

Conclusions:

  • The P-N component of the tPERG appears to reflect the accommodative response of the eye.
  • Age-related decline in accommodation is measurable using tPERG.
  • tPERG may serve as a valuable objective measure for assessing visual accommodation and its age-related changes.