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Mycobacterium avium antigenuria in patients with AIDS and disseminated M. avium disease
A A Sippola1, S L Gillespie, J A Lewis
1Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio.
The Journal of Infectious Diseases
|August 1, 1993
Abstract:
A 22,500-Da antigen apparently specific to Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum has been identified by Western immunoblotting. By use of a dot immunoassay, this antigen was found in the urine of 64% of patients with AIDS and disseminated M. avium disease. It was not found in the urine of healthy control subjects. Detection of antigenuria might provide the basis for rapid diagnosis of M. avium disease in patients with AIDS.