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[Sternocostoclavicular hyperostosis]

J T Gran1

  • 1Revmatologisk avdeling Aust-Agder Sentralsjukehus, Arendal.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|May 20, 1993
PubMed
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SAPHO syndrome, a condition involving inflammation and bone ossification, can manifest as sternocostoclavicular hyperostosis. This case report details a rare presentation in a young woman, successfully managed with anti-inflammatory medication.

Area of Science:

  • Rheumatology
  • Dermatology
  • Orthopedics

Background:

  • The synovitis, acne, pustulosis, hyperostosis, and osteomyelitis (SAPHO) syndrome encompasses a spectrum of disorders sharing clinical and radiological features.
  • Sternocostoclavicular hyperostosis, a component of SAPHO syndrome, involves inflammation and ossification affecting the sternoclavicular joints and anterior chest wall bones.

Observation:

  • A 20-year-old female presented with unilateral sternocostoclavicular hyperostosis and complete ankylosis of lumbar vertebrae (L2-L4).
  • Prior to musculoskeletal symptoms, the patient experienced transient scalp dermatitis and alopecia.

Findings:

  • The case illustrates a rare manifestation of SAPHO syndrome with extensive spinal involvement.
  • The patient's symptoms were effectively managed with non-steroidal anti-inflammatory drugs (NSAIDs), ketoprofen and naproxen.

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Implications:

  • This case expands the understanding of SAPHO syndrome's diverse clinical presentations.
  • Highlights the importance of considering SAPHO syndrome in young adults with inflammatory bone and joint conditions.
  • Demonstrates the efficacy of NSAIDs in managing symptoms of sternocostoclavicular hyperostosis.