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Clinical experience using the Bio-pump for extracorporeal circulation during open-heart surgery
1Department of Thoracic Surgery, Mie University School of Medicine, Japan.
Artificial Organs
|July 1, 1993
Summary
The Bio-pump offers a slight advantage over roller pumps in maintaining platelet function during open-heart surgery, with no significant differences in hemolysis or renal function. This makes the Bio-pump a potentially better choice for extracorporeal circulation.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Hemodynamics
Background:
- The Bio-pump is a widely used device in various clinical settings, including open-heart surgery and extracorporeal membrane oxygenation.
- Comparing the Bio-pump with traditional roller pumps is crucial for optimizing patient outcomes in cardiopulmonary bypass procedures.
Purpose of the Study:
- To compare the clinical efficacy of the Bio-pump versus the roller pump during open-heart surgery.
- To evaluate the impact of each pump on hemolysis, platelet function, and renal function in patients undergoing extracorporeal circulation.
Main Methods:
- A comparative study involving 21 patients undergoing open-heart surgery.
- Assessment of hemolysis, platelet function markers (platelet factor 4, beta-thromboglobulin), and renal function.
- Analysis of 6-keto-prostaglandin F1 alpha/thromboxane B2 ratio to evaluate platelet function.
Main Results:
- No significant difference in the amount of hemolysis between the Bio-pump and roller-pump groups.
- Platelet function was better preserved in the Bio-pump group, indicated by higher levels of specific platelet markers.
- No discernible differences in the impact on renal function between the two pump types.
Conclusions:
- The Bio-pump demonstrates a slight clinical advantage over roller pumps, primarily due to superior maintenance of platelet function.
- The findings suggest that the Bio-pump may be a preferable option for extracorporeal circulation in specific surgical contexts.