Transvaginal chorionic villus sampling using transabdominal ultrasound guidance: a new technique for first-trimester...

Transvaginal chorionic villus sampling (CVS) using concurrent transabdominal ultrasound guidance was performed in 20 women who desired CVS but could not be offered transcervical or transabdominal approaches because of uterine position and placental location. Satisfactory amounts of chorionic villi were obtained in all 20 cases with no maternal discomfort, an occurrence that contrasts with our experience in transvaginal CVS using endovaginal ultrasound guidance. We believe that transvaginal CVS using concurrent transabdominal ultrasound guidance warrants consideration as an alternative technique for first-trimester CVS in selected patients.