Related Experiment Video
Updated: Feb 6, 2026

Longitudinal Intravital Imaging Through Clear Silicone Windows
Published on: January 5, 2022
Adjuvanticity and arthritogenicity of silicone
1Department of Medicine, UCLA School of Medicine.
Abstract:
Potential adjuvanticity and arthritogenicity of silicone obtained from a mammary implant were investigated. Silicone, injected intraperitoneally in conjunction with heat-killed Mycobacterium tuberculosis and EL4 cells (mouse tumor cell, H-2b), failed to enhance the development of immune response directed toward EL4 cells in Lewis rats. Subplantar injection of silicone, alone or in combination with heat-killed M. tuberculosis, also failed to induce adjuvant arthritis in Lewis rats. These findings suggest that silicone has neither adjuvant activity nor arthritogenic property and is not an effective substitute for the mineral oil component of Freund's adjuvant.
Related Concept Videos
Network Covalent Solids
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Specific Heat
For example, increasing the temperature of one gram of water by 1°C requires one calorie of heat energy and can be written as 1 cal/g-°C, or...
Electron Affinity
Elements: Chemical Symbols and Isotopes
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
Band Theory
The energy difference between these bands is known as the band gap.
Conductor, Semiconductor,...
Polymers

