Related Experiment Video
Updated: Oct 9, 2026

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
Published on: February 16, 2015
Role of autotransplantation in treatment of other solid tumors
E J Shpall1, S M Stemmer, S I Bearman
1Division of Oncology, University of Colorado, Denver.
Abstract:
This article reviews the use of high-dose chemotherapy with autologous bone marrow support for a variety of solid tumors. A major feature of the vast majority of studies examined is the high response rates achieved with intensive therapy when compared with those reported with standard chemotherapy. If these rates can be obtained in patients with diseases refractory to standard therapy, then applying the same treatment earlier in the disease course may produce more durable antitumor effects.
Related Concept Videos
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Tumor Immunotherapy

