Related Experiment Videos
Death from a morphine infusion during a sickle cell crisis
1Department of Pharmacology, Ohio State University College of Medicine, Columbus 43210-1239.
The Journal of Pediatrics
|August 1, 1993
Summary
Narcotics can worsen sickle cell crises by causing respiratory issues that enhance red blood cell sickling. Patient-controlled analgesia is recommended for managing pain during sickle cell crises.
Area of Science:
- Medical Science
- Pharmacology
- Hematology
Background:
- Opioid analgesics are commonly used for pain management in sickle cell disease.
- Prolonged infusions of narcotics may lead to adverse respiratory effects.
- These effects can potentially exacerbate sickle cell vaso-occlusive crises.