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Topical hyperbaric therapy for problem skin wounds

M C Heng1

  • 1Department of Medicine, UCLA San Fernando Valley Internal Medicine Program, Veterans Administration Medical Center, Sepulveda.

The Journal of Dermatologic Surgery and Oncology
|August 1, 1993
PubMed
Summary
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Topical hyperbaric oxygen therapy offers a safe and effective treatment for open wounds by promoting new blood vessel growth without systemic toxicity. This approach is cost-effective and can be used early in treatment for recalcitrant wounds.

Area of Science:

  • Wound healing research
  • Hyperbaric medicine
  • Vascular biology

Background:

  • Systemic hyperbaric oxygen therapy (HBOT) is the only known treatment to stimulate new blood vessel growth.
  • However, systemic HBOT carries risks of central nervous system and pulmonary toxicity.

Purpose of the Study:

  • To detail topical hyperbaric oxygen therapy (THOT) for treating difficult-to-heal open wounds.
  • To contrast THOT with systemic HBOT.

Main Methods:

  • Description and comparison of topical and systemic hyperbaric oxygen treatments.
  • Outline of the applications of topical hyperbaric oxygen therapy.

Main Results:

  • Topical hyperbaric oxygen therapy is specifically indicated for open wounds.

Related Experiment Videos

  • THOT demonstrates effectiveness in promoting wound healing.
  • Conclusions:

    • Topical hyperbaric oxygen therapy is a cost-effective treatment with no systemic oxygen toxicity.
    • Its effectiveness allows for early application in managing recalcitrant open wounds, unlike systemic HBOT.