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Biologic skin substitutes
1Department of Dermatology, Boston University School of Medicine, Massachusetts 02118.
The Journal of Dermatologic Surgery and Oncology
|August 1, 1993
Abstract
Background:
The ideal skin substitute should closely approximate the skin in function. The substitute should be readily available, easily sterilized and stored, and relatively inexpensive.
Objective:
To describe recent developments in the area of biologic skin substitutes.
Results:
Considerable advances have been made in keratinocyte and fibroblast culturing when used in conjunction with a biodegradable material as a substrate.
Conclusion:
There is no skin substitute that perfectly mimics autologous skin. However, recent developments show promise.