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Lung function in Malay children

Y Ismail1, N N Azmi, Y Zurkurnain

  • 1Department of Medicine, Universiti Hospital, Kubang Kerian, Kelantan.

The Medical Journal of Malaysia
|June 1, 1993
PubMed
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This study measured lung function in Malay children aged 7-12, finding peak expiratory flow rate (PEFR), forced vital capacity (FVC), and forced expiratory volume in 1 second (FEV1) correlate with height. Malay children showed lower lung function compared to Western and Chinese cohorts.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Physiology
  • Public Health

Background:

  • Establishing normative lung function data is crucial for identifying respiratory abnormalities in children.
  • Malay children represent a distinct ethnic group for whom specific lung function reference values are needed.
  • Previous studies have highlighted ethnic variations in lung function parameters.

Purpose of the Study:

  • To measure peak expiratory flow rate (PEFR), forced vital capacity (FVC), and forced expiratory volume in 1 second (FEV1) in healthy Malay primary school children.
  • To develop prediction equations for these lung function indices specific to Malay children.
  • To compare lung function values of Malay children with those of other ethnic groups.

Main Methods:

  • Cross-sectional study involving 920 Malay primary school children (aged 7-12 years) for PEFR measurements.

Related Experiment Videos

  • Spirometry performed on 292 children to assess FVC and FEV1.
  • Statistical analysis to determine correlations between lung function parameters, age, and height.

    • Main Results:

    • PEFR showed significant correlations with both age and height.
    • FVC and FEV1 were significantly correlated with height only.
    • Prediction equations for PEFR, FVC, and FEV1 were formulated for Malay boys and girls.
    • Lung function values in Malay children were found to be lower than those reported for Western and Chinese children.

    Conclusions:

    • Height is a key determinant for lung function (FVC, FEV1) in Malay children, while age also influences PEFR.
    • The developed prediction equations provide ethnic-specific reference values for assessing respiratory health in Malay children.
    • The lower lung function observed in Malay children warrants further investigation into potential contributing factors.