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[Disseminated encephalomyelitis. A study of 5 cases]
F Coret1, T Sevilla, J J Vílchez
1Unidad de Neurología, Hospital Francisco de Borja de Gandía, Valencia.
Neurologia (Barcelona, Spain)
|June 1, 1993
Summary
Acute disseminated encephalomyelitis (ADE) can present variably, sometimes mimicking tumors. Steroid treatment effectively improved symptoms and lesion resolution in all cases.
Area of Science:
- Neurology
- Immunology
Background:
- Acute disseminated encephalomyelitis (ADE) is an immune-mediated demyelinating disease.
- Understanding its varied presentations is crucial for timely diagnosis and management.
Observation:
- Presents five cases of ADE with over 5 years of follow-up.
- Clinical and imaging findings (CT, MRI, LCR, evoked potentials) were highly variable.
- Two cases showed a pseudotumoral pattern, complicating diagnosis.
Findings:
- Symptoms preceded by viral infection in two cases.
- Disease course varied from acute (one case) to subacute (four cases).
- Clinical improvement correlated with partial resolution of demyelinating lesions.
Implications:
- Steroid therapy demonstrated efficacy in improving symptomatology and lesion resolution.
- Recognizing diverse ADE presentations can prevent unnecessary, aggressive diagnostic procedures.