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Liquid chromatographic study of the stability of 5-halogeno-2'-deoxyuridines
A Van Schepdael1, N Ossembe, P Herdewijn
1Katholieke Universiteit Leuven, Instituut voor Farmaceutische Wetenschappen, Belgium.
Journal of Pharmaceutical and Biomedical Analysis
|April 1, 1993
Abstract:
The stability of a series of 5-halogeno-2'-deoxyuridines was investigated using liquid chromatography as the analytical technique. Characteristics and profiles of the acidic, neutral and alkaline degradation are described, together with Arrhenius relationships and activation parameters for weakly acidic media.