The acalculous gallbladder

There is a definite clinical entity of chronic acalculous cholecystitis that can be cured by cholecystectomy. More research needs to be done on how this condition could be more accurately and earlier diagnosed. The majority of chronic gallbladder symptoms are not dependent on the presence of calculi. Gallbladder x-ray films are subject to significant diagnostic error, as are all other diagnostic tests. There is a need for more uniformity among pathologists as to what microscopic findings substantiate a diagnosis of chronic cholecystitis.