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Occupational dermatitis from isothiazolinones in the nylon production
R Valsecchi1, P Leghissa, S Piazzolla
1Department of Dermatology, Ospedali Riuniti di Bergamo, Italy.
Dermatology (Basel, Switzerland)
|January 1, 1993
Summary
Occupational allergic contact dermatitis can result from exposure to isothiazolinones, a biocide mixture used in industrial applications. This study observed six cases in a textile industry setting due to its use in nylon production.
Area of Science:
- Dermatology
- Occupational Health
- Industrial Hygiene
Background:
- Isothiazolinones are biocides used in various industries.
- They are effective against a broad spectrum of microorganisms.
- Previous cases of contact allergy have been reported from cosmetics and industrial products.
Purpose of the Study:
- To report on occupational allergic contact dermatitis caused by an isothiazolinone mixture.
- To investigate the role of isothiazolinones in a textile industry setting.
Main Methods:
- Observation of six cases of allergic contact dermatitis.
- Identification of the causative agent as an isothiazolinone mixture (Grotan TK 2).
- Analysis of the industrial application in a textile nylon production facility.
Main Results:
- Six cases of occupational allergic contact dermatitis were identified.
- The exposure was linked to an oil emulsion containing isothiazolinones used in the spinning phase.
- The biocide is used to prevent bacterial contamination and reduce yarn defects.
Conclusions:
- Isothiazolinone mixtures can cause occupational allergic contact dermatitis.
- Industrial hygiene practices should consider the potential for sensitization.
- Further investigation into safe handling and alternatives may be warranted.