Autoregulation of renal blood flow during halothane anesthesia

Renal blood flow, when not affected by humoral or neural influences, remains relatively constant over a wide range of renal arterial perfusion pressures. This phenomenon, referred to as "autoregulation," is an important mechanism allowing kidneys to maintain homeostasis of the internal milieu over a wide range of arterial pressures. The present study showed that 0.9 per cent halothane had no effect on autoregulation in an isolated, perfused dog kidney as renal arterial perfusion pressure was varied between 75 and 125 torr.