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Published on: July 19, 2018
Peritoneal dialysis in children. Review of 8 years' experience
Insights
Peritoneal dialysis is an effective treatment for acute renal failure in children. While peritoneal infection is a common complication, especially in younger children, it is generally treatable.
Area of Science:
- Pediatric Nephrology
- Critical Care Medicine
Background:
- Acute renal failure (ARF) in children presents significant management challenges.
- Peritoneal dialysis (PD) offers a therapeutic option for pediatric ARF.
Purpose of the Study:
- To evaluate the efficacy and safety of peritoneal dialysis in pediatric patients with acute renal failure.
- To identify common complications and outcomes associated with PD in this population.
Main Methods:
- Retrospective analysis of 59 PD sessions in 44 children (2 days to 17 years) from 1968-1975.
- Detailed review of complications, treatment strategies, and patient outcomes.
Main Results:
- Peritoneal infection was the most frequent complication (68% in <2 years, 30% in older children), typically responsive to treatment.
- Intramuscular and intraperitoneal gentamicin therapy was utilized.
- Mortality occurred in 2 patients due to intraperitoneal hemorrhage; one patient had intestinal perforation.
Conclusions:
- Peritoneal dialysis is a viable and safe method for managing pediatric ARF when performed in specialized centers.
- Experienced centers can effectively manage complex metabolic issues and underlying renal diseases during PD treatment.
Abstract:
During the years 1968-75, 59 periods of peritoneal dialysis were performed on 44 children aged from 2 days to 17 years. The commonest complication was peritoneal infection, which affected 68% of those under 2 years and 30% of older children. This was satisfactorily treated in all but one case which was due to Candida albicans. The use of combined intramuscular and intraperitoneal gentamicin therapy is described. 2 patients died as a result of massive intraperitoneal haemorrhage and one had a nonfatal intestinal perforation. In experienced hands peritoneal dialysis is a convenient, effective, and reasonably safe way of treating acute renal failure; it is best performed in centres capable of handling complex metabolic problems and investigating and treating the underlying renal disease.
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