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Related Experiment Videos

Electron microscopic changes in human pulps after intraligamental injection

M Torabinejad1, D L Peters, N Peckham

  • 1Loma Linda University, School of Dentistry, Calif.

Oral Surgery, Oral Medicine, and Oral Pathology
|August 1, 1993
PubMed
Summary

Intraligamental injection, a popular dental anesthesia technique, was studied for its effects on human pulps. Findings indicate that this method has no long-term adverse effects on young premolar pulps.

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Area of Science:

  • Dentistry
  • Oral Biology
  • Anesthesiology

Background:

  • Intraligamental injection is increasingly favored for dental anesthesia due to its benefits.
  • Concerns exist regarding potential adverse effects of intraligamental injections on human dental pulps.

Purpose of the Study:

  • To investigate the potential short-term and long-term effects of intraligamental injections on human dental pulps using electron microscopy.
  • To compare the cellular response of pulps following intraligamental anesthesia versus traditional nerve or field blocks.

Main Methods:

  • Forty-two human premolars scheduled for orthodontic extraction were anesthetized using intraligamental injections of 2% lidocaine with epinephrine.
  • Control teeth received the same anesthetic via nerve or field blocks.

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  • Pulp samples were examined under electron microscopy after varying post-injection periods (15 minutes to 28 days) and after simulated ischemia.

    • Main Results:

    • Minimal to no cellular changes were observed in the odontoblastic layer of pulps subjected to intraligamental injections.
    • In contrast, pulps exposed to simulated ischemia showed nuclear and cytoplasmic changes within an hour.
    • No significant long-term deleterious effects were detected in the experimental or control groups.

    Conclusions:

    • Intraligamental injection, when using standard anesthetic solutions, appears to be safe for human premolar pulps.
    • The technique does not induce significant cellular damage or long-term harm to the dental pulp.
    • Further research may explore different anesthetic agents or patient populations.