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Published on: February 18, 2012
Episodes of bradycardia during early infancy in the term-born and preterm infant
J E Hodgman1, T Hoppenbrouwers, L A Cabal
1Division of Neonatology, Los Angeles County+University of Southern California Medical Center 90033.
Insights
Transient episodes of bradycardia are common in infants up to six months old and are normal reflex responses. These findings suggest that bradycardia episodes are not linked to sudden infant death syndrome risk.
Area of Science:
- Neonatal physiology
- Pediatric cardiology
- Sleep medicine
Background:
- Transient bradycardia episodes are common in infants.
- Understanding these events is crucial for differentiating normal physiology from pathology.
Purpose of the Study:
- To document the incidence of transient bradycardia in healthy term and preterm infants.
- To explore the relationship between bradycardia, apnea, oxygen levels, and sleep state.
Main Methods:
- Longitudinal polysomnographic study in a sleep laboratory.
- Included 14 term infants and 19 preterm infants (9 with apnea, 10 without).
- Analyzed 2-4 hour polysomnographic tracings for bradycardia episodes (< or = 100 bpm).
Main Results:
- Transient bradycardia (60-70 bpm) was common, with no drops below 50 bpm.
- Incidence of bradycardia was inversely related to heart rate.
- Apneic and nonapneic preterm infants showed similar results.
Conclusions:
- Transient bradycardia episodes are normal reflex responses in infants.
- These episodes are not associated with an increased risk of sudden infant death syndrome (SIDS).
- Findings have implications for setting infant monitor alarms.
Objective:
To document the incidence of transient episodes of bradycardia in a group of healthy term and preterm infants during the first 1 to 6 months of life.
Design:
Longitudinal polysomnographic study.
Setting:
Sleep laboratory in a university-affiliated urban medical center.
Participants:
Fourteen healthy term-born infants, nine preterm infants with apnea in the nursery, and 10 preterm infants without apnea. Infants with neonatal morbidity except apnea were excluded.
Measurements:
Transient episodes of bradycardia (< or = 100 beats per minute) were identified in 2- to 4-hour early evening polysomnographic tracings. The relationship with apnea, transcutaneous oxygen levels, and sleep state was determined.
Results:
Transient episodes of bradycardia to 60 to 70 beats per minute were common, but there were no drops below 50 beats per minute. The incidence of transient episodes of bradycardia was inversely related to heart rate. Results for apneic and nonapneic premature infants were similar.
Conclusions:
Transient episodes of bradycardia are considered normal reflex responses and are not related to risk for sudden infant death syndrome. These results have implications for the setting of monitor alarms.
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