[Epiphyseal interrelations with the striatum in the haloperidol-induced catalepsy model]

Removal of the rat pineal gland entailed an attenuation of haloperidol-induced catalepsy and readjustment of its time-course. This may depend on either direct of indirect effects of the pineal factors, mostly in the ventral portion of the striatum whose hyperactivity determines the main parameters of the neuroleptic effect.