Drug-induced pemphigus
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D F Mutasim1, N J Pelc, G J Anhalt
1Department of Dermatology, University of Cincinnati Medical Center, Ohio.
Dermatologic Clinics
|July 1, 1993
Abstract:
Drug-induced pemphigus is a heterogenous group of disorders in which a drug induces acantholysis. The majority of patients have immune features of pemphigus and have a course similar to idiopathic pemphigus. Few patients do not have a detectable autoimmune process, and their eruption usually resolves with discontinuation of the associated drug. The mechanism of induction of the autoimmune process and acantholysis is not clear.