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Reactive corneal endothelialization

N J Colosi, M Yanoff

    American Journal of Ophthalmology
    |February 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Corneal endothelialization of the anterior chamber angle occurred in 22% of enucleated eyes. This finding was often overlooked in initial pathological assessments, highlighting a need for careful examination in ocular pathology studies.

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    Area of Science:

    • Ophthalmology
    • Pathology
    • Corneal Science

    Background:

    • Corneal endothelialization of the anterior chamber angle is a recognized pathological finding.
    • Its incidence and clinical significance require further elucidation, particularly in post-enucleation specimens.

    Purpose of the Study:

    • To determine the incidence of corneal endothelialization of the anterior chamber angle in a series of enucleated globes.
    • To assess whether this finding was adequately reported in original pathological descriptions.

    Main Methods:

    • Retrospective review of 100 consecutive enucleated globes.
    • Histopathological examination of the anterior chamber angle.

    Main Results:

    • Corneal endothelialization of the anterior chamber angle was identified in 22% (22 out of 100) of the globes.

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  • In 15 of these 22 cases (68%), the endothelialization had been overlooked or not mentioned in the original pathological reports.

    • Conclusions:

    • Corneal endothelialization of the anterior chamber angle is a relatively common finding in enucleated globes.
    • Pathological descriptions of enucleated globes may frequently underreport this condition, necessitating increased awareness and meticulous examination.