Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Implantation and decidualization in rodents

P A Abrahamsohn1, T M Zorn

  • 1Department of Histology and Embryology, University of Sao Paulo, Brazil.

The Journal of Experimental Zoology
|September 1, 1993
PubMed
Summary

Embryo implantation involves uterine epithelial apoptosis and fibroblast transformation into decidual cells. These decidual cells support pregnancy by synthesizing molecules and remodeling the extracellular matrix.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Osteocalcin improves insulin resistance and inflammation in obese mice: Participation of white adipose tissue and bone.

Bone·2017
Same author

Long-term type 1 diabetes impairs decidualization and extracellular matrix remodeling during early embryonic development in mice.

Placenta·2013
Same author

Stat3 and Socs3 expression patterns during murine placenta development.

European journal of histochemistry : EJH·2013
Same author

An ultrastructural observation on charquis, salted and intermediate moisture meat products.

Meat science·2011
Same author

Maternal diabetes affects specific extracellular matrix components during placentation.

Journal of anatomy·2007
Same author

Characterization and distribution of hyaluronan and the proteoglycans decorin, biglycan and perlecan in the developing embryonic mouse gonad.

Journal of anatomy·2007

Area of Science:

  • Reproductive Biology
  • Developmental Biology
  • Cell Biology

Background:

  • Embryo implantation and decidualization are critical early pregnancy events.
  • Rodent models are extensively used to study these complex processes.

Purpose of the Study:

  • To review the key events and molecular mechanisms of embryo implantation and decidualization in rodents.
  • To highlight the cellular transformations and signaling pathways involved.

Main Methods:

  • Review of existing literature on rodent embryo implantation and decidualization.
  • Analysis of cellular morphology and molecular changes during decidualization.

Main Results:

  • Embryo attachment triggers uterine epithelial apoptosis and underlying fibroblast differentiation into decidual cells.
  • Decidual cells exhibit enhanced synthesis of macromolecules, form intercellular junctions, and remodel the extracellular matrix.
  • Decidualization involves signaling molecules like prostaglandins, leukotrienes, platelet-activating factor, and transforming growth factor.

Conclusions:

  • Decidualization is a dynamic process involving significant cellular and molecular changes essential for pregnancy support.
  • Rodent models provide valuable insights into the fundamental mechanisms of implantation and decidualization.

Related Experiment Videos