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Related Experiment Videos

Think cutaneous leishmaniasis

B Amichai1, E Finkelstein, M H Grunwald

  • 1Department of Dermatology, Soroka Medical Centre of Kupat Holim.

Australian Family Physician
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

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Cutaneous leishmaniasis is increasingly diagnosed in non-endemic regions, particularly among travelers and military personnel. This review details its clinical signs, diagnostic methods, and therapeutic strategies.

Area of Science:

  • Medical Parasitology
  • Infectious Diseases
  • Dermatology

Background:

  • Cutaneous leishmaniasis (CL) is a neglected tropical disease caused by protozoan parasites of the genus Leishmania.
  • CL is endemic in parts of the Middle East, Central and South America, and Africa.
  • Recent geopolitical events have led to an increase in CL cases among travelers and military personnel returning from endemic areas.

Purpose of the Study:

  • To review the clinical manifestations of cutaneous leishmaniasis.
  • To outline the diagnostic laboratory findings for CL.
  • To discuss current and emerging treatment options for CL.

Main Methods:

  • Literature review of clinical studies, case reports, and treatment guidelines on cutaneous leishmaniasis.
  • Analysis of epidemiological data regarding CL in non-endemic regions.

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  • Synthesis of information on diagnostic techniques and therapeutic interventions.

    • Main Results:

    • CL presents with diverse skin lesions, including papules, nodules, and ulcers, varying in morphology and chronicity.
    • Diagnosis relies on microscopic examination of Giemsa-stained smears, culture, or molecular methods (PCR).
    • Treatment options range from topical agents and intralesional injections to systemic therapy, with drug resistance being a concern.

    Conclusions:

    • Cutaneous leishmaniasis poses a growing public health challenge in non-endemic regions due to increased travel and military deployment.
    • Early diagnosis and appropriate treatment are crucial to prevent complications and transmission.
    • Further research into novel therapeutic strategies and diagnostic tools is warranted.