Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Olfactory information processing and temporal lobe epilepsy

B Carroll1, J T Richardson, P Thompson

  • 1Department of Human Sciences, Brunel University, Uxbridge, Middlesex, UK.

Brain and Cognition
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

What kind of illness is anorexia nervosa? Revisited: some preliminary thoughts to finding a cure.

Journal of eating disorders·2023
Same author

Toxicological Evaluation of β-Caryophyllene Oil: Subchronic Toxicity in Rats.

International journal of toxicology·2016
Same author

P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest.

Cell death & disease·2015
Same author

MEASURING INTER-HEMISPHERIC INTEGRATION IN BIPOLAR AFFECTIVE DISORDER USING BRAIN NETWORK ANALYSES AND HARDI.

Proceedings. IEEE International Symposium on Biomedical Imaging·2012
Same author

Recent developments in random sample tests for poultry in the united kingdom.

Annales de genetique et de selection animale·2012
Same author

HLA-DPβ1 Asp84-Lys69 antigen-binding signature predicts event-free survival in childhood B-cell precursor acute lymphoblastic leukaemia: results from the MRC UKALL XI childhood ALL trial.

Blood cancer journal·2012
Same journal

Gelastic dysarthria: Speech-triggered pathological laughter with evidence for a selective pontine gating mechanism.

Brain and cognition·2026
Same journal

Brain correlates of linguistic-cognitive stimulation in neurotypical and Atypical older adult populations: A systematic review.

Brain and cognition·2026
Same journal

Effects of Dieting on Neural Encoding of Preferences for Edible and Non-Edible Rewards: An ERP Study.

Brain and cognition·2026
Same journal

Structural complexity of brain regions in mild cognitive impairment and Alzheimer's disease.

Brain and cognition·2026
Same journal

Spatial navigation training enhances performance on large-scale and small-scale spatial tasks through different neural mechanisms.

Brain and cognition·2026
Same journal

Unraveling the link between brain injury and enhanced artistic skills.

Brain and cognition·2026
See all related articles

Patients with temporal lobe epilepsy show olfactory impairments, particularly in odor identification and memory retention. Right temporal lobe epilepsy specifically affects the recall of odor-associated memories.

Area of Science:

  • Neuroscience
  • Epilepsy Research
  • Olfactory Processing

Background:

  • Olfactory information processing may be impaired in temporal lobe epilepsy (TLE).
  • Existing evidence is conflicting regarding the extent and nature of olfactory deficits in TLE.
  • Understanding these deficits is crucial for diagnosing and managing TLE.

Purpose of the Study:

  • To investigate olfactory information processing in patients with TLE.
  • To compare odor identification and retention across different epilepsy groups (left TLE, right TLE, non-temporal epilepsy) and controls.
  • To determine if specific epilepsy locations correlate with distinct olfactory deficits.

Main Methods:

  • Comparison of patients with epileptogenic foci in the left temporal lobe, right temporal lobe, or other brain regions with normal control subjects.

Related Experiment Videos

  • Assessment of odor identification (verbal labeling) and odor retention (immediate recognition memory).
  • Analysis of performance differences between patient groups and controls.

    • Main Results:

    • All three patient groups (left TLE, right TLE, non-temporal epilepsy) exhibited significant and equal impairment in verbally labeling odors.
    • Patients with left TLE or non-temporal epilepsy showed no impairment in immediate recognition memory for odors.
    • Patients with right TLE demonstrated a specific deficit in retaining the memory of nameable odors.

    Conclusions:

    • Olfactory deficits in TLE are not uniform and depend on the epilepsy's location.
    • Right TLE is associated with a specific impairment in the retention of nameable odors.
    • This deficit in right TLE may stem from difficulties in retrieving episodic memories crucial for odor context encoding.