Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peptide libraries: criteria and trends

R A Houghten1

  • 1Torrey Pines Institute for Molecular Studies, San Diego, CA 92121.

Trends in Genetics : TIG
|July 1, 1993
PubMed
Summary

Researchers develop methods to create vast peptide libraries with millions of sequences. These libraries are crucial for understanding molecular interactions and discovering new bioactive peptides.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Affinity purification of ?-endorphin-like material from NG108CC15 hybrid cells by means of the monoclonal ?-endorphin antibody 3-E7.

Neurochemistry international·2010
Same author

Solid phase synthesis of mixture-based acyclic and heterocyclic small molecule combinatorial libraries from resin-bound polyamides.

Biopolymers·2002
Same author

A novel approach for solid-phase synthesis of substituted imidazolines and bis-imidazolines.

The Journal of organic chemistry·2001
Same author

Solid-phase synthesis of alpha,alpha-difluoro-beta-amino acids via the Reformatsky reaction.

The Journal of organic chemistry·2001
Same author

Solid-phase synthesis of 2,3,5-trisubstituted 4H-imidazolones.

Journal of combinatorial chemistry·2001
Same author

A novel approach for the solid-phase synthesis of substituted cyclic guanidines, their respective bis analogues, and N-acylated guanidines from N-acylated amino acid amides.

Journal of combinatorial chemistry·2001

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Drug Discovery

Background:

  • Peptide libraries are essential tools in molecular biology.
  • Understanding molecular interactions is key to biological processes.

Purpose of the Study:

  • To describe the development of methods for preparing large peptide libraries.
  • To highlight the utility of these libraries in characterizing molecular interactions and identifying novel bioactive sequences.

Main Methods:

  • Preparation of peptide libraries with millions of diverse amino acid sequences.
  • Utilizing these libraries for functional screening and characterization.

Main Results:

  • Successfully generated peptide libraries containing millions of distinct sequences.
  • Demonstrated the value of these libraries in studying molecular interactions.

Conclusions:

  • The developed methods provide an invaluable resource for biological research.
  • Peptide libraries are powerful tools for identifying sequences with desired biological activities.

Related Experiment Videos