[The level of middle molecules in determining the degree of intoxication in patients with suppurative wounds]

For the estimation of the intoxication degree an analysis of dynamics of the level of medium-sized molecules (LMM) in blood serum was made in 71 patients with purulent wounds in different courses of the wound process. The results obtained were compared with the parameters of bacteriological and cytological characteristics. It was found that the 1.5 times elevation of LMM with values up to 0.380 units spoke of the compensated degree of intoxication with the following favourable course and disappearance by the 5th day of the postoperative period. While the 2-3 times elevation of LMM parameters--up to 0.710 units lies outside the limits of compensatory potentialities and complex antibacterial therapy normalized them by the 9th day. The comparison of dynamics of the parameters studied shows their clear correlative relationship.