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Updated: Aug 18, 2026

Stretch in Brain Microvascular Endothelial Cells (cEND) as an In Vitro Traumatic Brain Injury Model of the Blood Brain Barrier
Published on: October 27, 2013
[Protective reaction of brain cells during change in permeability of the blood-brain barrier]
Abstract:
General anesthesia carried out in neurosurgical operations caused liberation of neurospecific proteins into blood. High content of these antigens was maintained in biological fluids within 7 days, which occurred apparently due to activation of biosynthesis. Antibodies to the antigens were detected only within 21 days after the surgical intervention. A gross liberation of specific proteins into blood, occurring under critical conditions, appears to be a protective response of brain cells to autoimmune impairments.
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