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Onychomycosis. Agents of choice
1St. John's Institute of Dermatology, Guy's Hospital, London, United Kingdom.
Abstract:
The management of onychomycosis has changed considerably in the past few years. The main trends have been improvement in the choice of evidence and cover of infections other than dermatophytosis, shortening of periods of oral therapy, and introduction of topical agents designed to treat nail disease. At present there have been almost no comparative studies of these different approaches, and choice is therefore largely based on enlightened guesswork coupled with personal experience. It is hoped that within the next few years such studies will be carried out to allow dermatologists to make an accurate choice based on appropriate scientific data.
Insights
Onychomycosis treatment has evolved with new evidence and topical agents. Comparative studies are lacking, making treatment choices based on experience rather than data.
Area of Science:
- Dermatology
- Mycology
- Infectious Diseases
Background:
- Onychomycosis management has seen significant recent changes.
- Trends include improved evidence, broader infection coverage, shorter oral therapies, and new topical agents.
- Current treatment selection relies heavily on clinical experience due to a lack of comparative data.
Purpose of the Study:
- To review current trends in onychomycosis management.
- To highlight the need for comparative studies to guide evidence-based treatment choices.
Main Methods:
- Review of recent advancements in onychomycosis treatment.
- Analysis of emerging trends in therapeutic approaches.
Main Results:
- Significant evolution in onychomycosis treatment strategies observed.
- Introduction of novel topical therapies for nail fungal infections.
- Shortening of systemic (oral) therapy durations noted.
Conclusions:
- The current landscape of onychomycosis treatment is dynamic.
- A critical need exists for comparative research to inform optimal therapeutic decisions.
- Future studies are anticipated to provide data for evidence-based dermatological practice.