Complete nucleotide sequence of the cDNA encoding rabbit coagulation factor VII
Related Experiment Video
Updated: Nov 7, 2026

The Lambda Select cII Mutation Detection System
Published on: April 26, 2018
A B Brothers1, B J Clarke, W P Sheffield
1Department of Pathology, McMaster University, Hamilton, Ontario, Canada.
Abstract:
Rabbit coagulation factor VII cDNA has been cloned and sequenced. Two rabbit liver cDNA libraries in lambda gt11 were screened using both random-primed, 32p-labelled, factor VII cDNAs and polymerase chain reaction technology. Three overlapping cDNA clones were isolated comprising a sequence of 1572 base pairs of DNA encoding an open-reading-frame of 443 amino acids. Mature circulating rabbit factor VII is predicted to contain 404 amino acids, two less than its human counterpart and three less than bovine factor VII.
Related Concept Videos
RACE - Rapid Amplification of cDNA Ends
Since the...
Complementary DNA
Complementary DNA
Rab Proteins
Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...
Recombinant DNA Technology
Recombinant DNA

