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The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene
H J Rode1, W Janssen, A Rösen-Wolff
1Institut für Medizinische Virologie, Universität Heidelberg, Germany.
Virus Genes
|February 1, 1993
Abstract:
A gene was identified within the DNA sequences of the EcoRI DNA fragment N (4.3 kbp) of the genome of equine herpesvirus type 2 (EHV-2) coding for a protein (179 amino acid residues) homologous to the cytokine synthesis inhibitory factor (CSIF; interleukin 10) of the human and mouse, and to the Epstein-Barr virus (EBV) protein BCRF1. This finding is further significant evidence that the interleukin 10 (IL-10) and/or IL-10-like gene can indeed be present in the genomes of members of the herpesviral family.