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Updated: Oct 14, 2026

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Published on: August 24, 2011
Rapid near IR spectrophotometric determination of meprobamate in pharmaceutical preparations
Journal of Pharmaceutical Sciences
|February 1, 1977
Abstract:
A rapid near IR spectrophotometric method was developed for determining meprobamate in tablets, sustained-release capsules, suspensions, and injectables. The absorbance of a chloroform solution of the drug is obtained at about 1.96 mum for quantitation. Assay of nine commercial products from four different manufacturers gave results ranging from 97 to 104% of label claim. Coefficients of variation of 0.7 and 1.3% were obtained on the tablets and a sustained-release product, respectively.

