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Features of systemic sclerosis (scleroderma) in an identical twin pair
N J Cook1, A J Silman, J Propert
1Rheumatology Unit, Southampton University Hospital, Manchester.
British Journal of Rheumatology
|October 1, 1993
Summary
Systemic sclerosis (scleroderma) has unknown causes, possibly genetic and environmental. This study reports identical twins and their mother all exhibiting features of this rare autoimmune disease.
Area of Science:
- Immunology
- Genetics
- Dermatology
Background:
- Systemic sclerosis (scleroderma) etiology remains largely unknown.
- Genetic and environmental factors are suspected contributors.
- Familial incidence is notably rare, with limited case reports in twins.