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Triphasic waves in myxedema coma

Y River1, O Zelig

  • 1Department of Neurology, Hadassah University Hospital, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

Clinical EEG (Electroencephalography)
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Triphasic waves, often seen in encephalopathies, were observed in a patient with myxedema coma. These brainwave patterns resolved after thyroid hormone replacement therapy.

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Area of Science:

  • Neurology
  • Endocrinology

Background:

  • Triphasic waves are characteristic electroencephalogram (EEG) findings associated with various encephalopathies.
  • These EEG abnormalities can occur in both metabolic and nonmetabolic causes of brain dysfunction.

Observation:

  • An elderly patient presented with clinical and EEG findings suggestive of encephalopathy.
  • The patient was diagnosed with myxedema coma, a severe form of hypothyroidism.

Findings:

  • Electroencephalogram (EEG) monitoring revealed the presence of triphasic waves in the patient.
  • These characteristic triphasic waves resolved completely following the initiation of thyroid hormone replacement therapy.

Implications:

  • This case highlights a previously unreported association between myxedema coma and triphasic waves.
  • The findings suggest that triphasic waves may be a potential EEG marker in severe hypothyroidism and can be reversible with treatment.