[Inflammatory syndrome, anicteric cholestasis and hepatic adenoma]
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Updated: Nov 7, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
Published on: February 10, 2015
B Berthet1, J M Escoffier, P J Weiller
1Service de Chirurgie générale et digestive, Hôpital de la Conception, Marseille.
Abstract:
An unusual form of adenoma of left lobe of liver was detected fortuitously in a young woman with an inflammatory syndrome and an anicteric cholestasis. In this case, a positive correlation existed between the adenoma and the treatment with estrogens, the disappearance of the biologic anomalies after exeresis of the adenoma being suggestive of an increased production of fibrinogen by hepatocytes. The cholestasis was probably the result of pressure exerted by the adenoma. Excision of the adenoma was justified by the risk of hemorrhagic complications and the possibility of malignant changes in the tumor.
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