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Updated: Aug 19, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Abstract:
A study of the survival and prognosis of renal cancer was performed in 97 patients in different stage of the disease. Mean survival was 2.9 years for males and 3.1 years for females (no statistical significance as to sex). It was shown that with advancing stage of the disease decreased patient survival (T-2 = 4.1 yrs., T-3A = 2.5 yrs., T-3B = 1.3 yrs). The same tendency was observed to a higher degree in N-stage, according to the TNM classification: no single patient survived in N-2 stage beyond 3 years. Observations in M-2 stage showed a much shorter survival time: there was no survival beyond 1 year in M-2 stage.
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