Heparin vs. saline for peripheral i.v. locks in children

Area of Science:

• Pediatric Nursing
• Intravenous Therapy
• Pharmacology

Background:

• Maintaining patency of peripheral intravenous (IV) locks is crucial in pediatric care.
• Heparin flush solution is commonly used, but saline is a potential alternative.
• Evidence comparing saline and heparin efficacy in pediatric populations is limited.

Purpose of the Study:

• To compare the efficacy of saline versus heparin flush solutions.
• To determine the best method for maintaining peripheral IV lock patency in pediatric patients.

Main Methods:

• Prospective, randomized, double-blind study design.
• 124 pediatric patients (infants >28 days and children) with peripheral IVs.
• IVs were flushed with either saline or heparinized saline.

Main Results:

• No significant difference in the total duration of IV use between groups.
• Comparable incidence of complications (e.g., occlusion, phlebitis) between saline and heparin groups.
• Saline demonstrated equivalent efficacy in maintaining IV lock patency.

Conclusions:

• Saline is an effective and safe alternative to heparin for flushing peripheral IV locks in pediatric patients over 28 days of age.
• Saline flushes can be confidently used to maintain pediatric peripheral IV patency.
• Further research may explore cost-effectiveness and long-term outcomes.