Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ear length in second-trimester aneuploid fetuses

L Lettieri1, J F Rodis, A M Vintzileos

  • 1Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington.

Obstetrics and Gynecology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Restrictive interventions on a psychiatric admission ward before and after COVID-19.

Irish journal of psychological medicine·2022
Same author

COVID-19 from the perspective of urban and rural general adult mental health services.

Irish journal of psychological medicine·2020
Same author

Changing prescribing patterns in an Irish community mental health service.

Irish journal of psychological medicine·2020
Same author

Should all community mental health teams be sectorised?

Irish journal of psychological medicine·2020
Same author

Snap-valve cerebral shunt design for intracranial pressure operation and ultrasound visualization.

Medical engineering & physics·2019
Same author

Intrapartum cardiotocography has become the standard of care even in low-risk pregnancies.

BJOG : an international journal of obstetrics and gynaecology·2018

Small fetal ear length may help detect aneuploidy in the second trimester. Ultrasound measurements of ear length showed 71% sensitivity and 92% specificity in identifying fetuses with chromosomal abnormalities.

Area of Science:

  • Prenatal diagnosis
  • Medical imaging
  • Genetics

Background:

  • Aneuploidy, such as Down syndrome, is a common concern in prenatal diagnosis.
  • Ultrasound is a key tool for assessing fetal well-being and detecting anomalies.

Purpose of the Study:

  • To evaluate the diagnostic utility of fetal ear length in identifying second-trimester aneuploid fetuses using ultrasound.
  • To establish a nomogram for fetal ear length across gestational ages.

Main Methods:

  • Prospective study of 482 singleton pregnancies undergoing ultrasound between 14-25 weeks.
  • Standard fetal biometry, including ear length, was measured.
  • Genetic amniocentesis was performed for aneuploidy testing.

Main Results:

Related Experiment Videos

  • A nomogram for ear length by gestational age was created (r = 0.84).
  • Ten of fourteen aneuploid fetuses had ear lengths at or below the tenth percentile.
  • Ultrasound ear length measurement demonstrated 71% sensitivity and 92% specificity for aneuploidy detection.

Conclusions:

  • Fetal ear length measurement by ultrasound may serve as a valuable screening tool for aneuploidy in the second trimester.
  • Sonographic assessment of ear length can aid in identifying fetuses at higher risk for chromosomal abnormalities.