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The West Midlands epithelial ovarian cancer adjuvant therapy trial
C W Redman1, J Mould, J Warwick
1West Midlands CRC Clinical Trials Unit, Queen Elizabeth Medical Centre, Birmingham, UK.
Abstract:
In a multicentre prospective randomized controlled trial, single agent cisplatinum was compared with whole abdomino-pelvic moving strip radiotherapy in the management of Stage IC-III epithelial ovarian cancer patients who had no macroscopic residual disease after primary surgery. Over a 6-year period 40 eligible patients were recruited, 15 of whom had Stage III disease. The overall 5-year survival was 60% with no significant survival difference between the treatment groups. Acute toxicity was common in both arms and six (11%) patients experienced significant long term disability.