Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allopurinol-induced toxic pustuloderma

R C Yu1, T C Chu

  • 1Unit of Dermatology, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.

The British Journal of Dermatology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cochlear device explantation in patients with nasopharyngeal cancer irradiation.

Cochlear implants international·2025
Same author

Zhou et al. Reply.

Physical review letters·2024
Same author

Octahedral Distortion and Displacement-Type Ferroelectricity with Switchable Photovoltaic Effect in a 3d^{3}-Electron Perovskite System.

Physical review letters·2023
Same author

Li(Cd,Mn)P: a new cadmium based diluted ferromagnetic semiconductor with independent spin & charge doping.

Scientific reports·2019
Same author

Oxygen defect engineering by the current effect assisted with temperature cycling in a perovskite-type La<sub>0.7</sub>Sr<sub>0.3</sub>CoO<sub>3</sub> film.

Nanoscale·2017
Same author

Origin of atomic displacement in HAADF image of the tilted specimen.

Ultramicroscopy·2017
Same journal

Does loss of chromosome Y in blood contribute to the sex disparity of dermatitis and eczema at older ages?

The British journal of dermatology·2026
Same journal

Soluble CD83 reverses alopecia areata via IDO-mediated Treg cell activation.

The British journal of dermatology·2026
Same journal

Durability of Response to Icotrokinra in Adults With Moderate-to-Severe Plaque Psoriasis: One-Year Results From the Phase 3, Placebo- and Active Comparator-Controlled ICONIC-ADVANCE 1 & ICONIC-ADVANCE 2 Trials.

The British journal of dermatology·2026
Same journal

Clinicopathological features of lymphocytic thrombophilic arteritis and the relationship with livedoid vasculopathy - a case series of 36 patients.

The British journal of dermatology·2026
Same journal

Improving Prognostication for Cutaneous Squamous Cell Carcinoma.

The British journal of dermatology·2026
Same journal

Recurrent and novel GLTP variants in five patients with nonsyndromic epidermal differentiation disorder: phenotypic and genotypic expansion.

The British journal of dermatology·2026
See all related articles

Allopurinol can cause toxic pustuloderma, a rare skin reaction. This case highlights a new drug association for this severe generalized pustular eruption.

Area of Science:

  • Dermatology
  • Toxicology
  • Pharmacology

Background:

  • Toxic pustuloderma is an uncommon generalized pustular eruption.
  • Various medications have been implicated in its development.
  • Allopurinol is a commonly prescribed medication for gout and hyperuricemia.

Observation:

  • A 67-year-old male presented with fever, neutrophilia, eosinophilia, and a pustular eruption.
  • The patient had recently completed a short course of allopurinol.
  • Clinical and pathological features were consistent with toxic pustuloderma.

Findings:

  • This is the first reported case of toxic pustuloderma associated with allopurinol.
  • The temporal relationship suggests allopurinol as the causative agent.
  • The patient's presentation included characteristic signs of toxic pustuloderma.

Related Experiment Videos

Implications:

  • This finding expands the list of potential drug triggers for toxic pustuloderma.
  • Clinicians should consider allopurinol as a possible cause in patients presenting with these symptoms.
  • Further investigation into the mechanism of allopurinol-induced toxic pustuloderma may be warranted.