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Dihydroxyacetone test as a substitute for the dansyl chloride test
G E Piérard1, C Piérard-Franchimont
1Department of Dermatopathology, University of Liège, Belgium.
Dermatology (Basel, Switzerland)
|January 1, 1993
Abstract:
The hazards of the dansyl chloride test are not negligible. We introduce the dihydroxyacetone test as a safe substitute. Several advantages are highlighted including easy and reproducible measurements of the modifications in skin color by chromometry in the L* a* b* (luminance, hue, chroma) mode. The color variations in time as well as the fade-out of DHA-induced pigmentation by some cleansing skin care products are revealed 'in vivo' as well as 'ex vivo' on D-Squame collections of stratum corneum.