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Sandramycin, a novel antitumor antibiotic produced by a Nocardioides sp. II. Structure determination
J A Matson1, K L Colson, G N Belofsky
1Bristol-Myers Squibb, Pharmaceutical Research Institute, Wallingford, CT 06492.
The Journal of Antibiotics
|January 1, 1993
Abstract:
The structure of sandramycin, a novel antitumor antibiotic, was established by spectroscopic analysis and chiral chromatography of its acid hydrolysate. It was determined to be a cyclic decadepsipeptide with a two-fold axis of symmetry and 3-hydroxyquinaldic acid as an appended chromophore.