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Zinc abuse and sideroblastic anemia
J Ramadurai1, C Shapiro, M Kozloff
1Department of Medicine, Humana Hospital-Michael Reese, Chicago.
American Journal of Hematology
|February 1, 1993
Summary
Excessive zinc intake can cause anemia and leukopenia by disrupting copper levels, leading to ringed sideroblasts. Discontinuing zinc supplements resulted in complete hematologic recovery, highlighting the importance of trace metal balance.
Area of Science:
- Hematology
- Nutritional Science
- Toxicology
Background:
- Anemia and leukopenia are common hematologic abnormalities.
- Trace metals play a crucial role in maintaining normal hematopoiesis.
- Imbalances in essential trace elements can lead to adverse health effects.