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Synovial copper deposition as a possible explanation of arthropathy in Wilson's disease
U Kramer1, A Weinberger, R Yarom
1Department of Internal Medicine B, Beilinson Medical Center, Petah Tiqva, Israel.
Bulletin (Hospital for Joint Diseases (New York, N.Y.))
|January 1, 1993
Abstract:
A patient with longstanding Wilson's disease and arthritis is presented. Synovial biopsy disclosed thickening of the membrane, intimal histiocytes, and lymphocyte infiltration without pigmentation. X-ray energy spectroscopy demonstrated copper and iron in high concentrations. These findings may contribute to our understanding of the development of the arthropathy in patients with Wilson's disease.